238000000206 photolithography Methods 0.000 claims description 7.108010001801 Tumor Necrosis Factor-alpha Proteins 0.000 claims description 7.102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims description 7.238000004519 manufacturing process Methods 0.000 claims description 8.230000003746 surface roughness Effects 0.000 claims description 10.230000000144 pharmacologic effect Effects 0.000 claims description 20.150000001875 compounds Chemical class 0.000 claims description 43.239000002086 nanomaterial Substances 0.000 claims description 45.108090000623 proteins and genes Proteins 0.000 claims description 67.102000004169 proteins and genes Human genes 0.000 claims description 67. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Priority to US32872310P priority Critical Priority to US41107110P priority Priority to US201161435939P priority Application filed by Kimberly Clark Co filed Critical Kimberly Clark Co Publication of PT2563453T publication Critical patent/PT2563453T/en Links Inventor Frederick Ross Russell Original Assignee Kimberly Clark Co Priority date (The priority date is an assumption and is not a legal conclusion. Google Patents Nanopatterned medical device with enhanced cellular interaction and method for its formingÄownload PDF Info Publication number PT2563453T PT2563453T PT117745216T PT11774521T PT2563453T PT 2563453 T PT2563453 T PT 2563453T PT 117745216 T PT117745216 T PT 117745216T PT 11774521 T PT11774521 T PT 11774521T PT 2563453 T PT2563453 T PT 2563453T Authority PT Portugal Prior art keywords nanostructures nanometers medical device cells microneedle Prior art date Application number PT117745216T Other languages Portuguese ( pt) Google Patents PT2563453T - Nanopatterned medical device with enhanced cellular interaction and method for its forming PT2563453T - Nanopatterned medical device with enhanced cellular interaction and method for its forming
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